Epitope-Tagged P(0)Glycoprotein Causes Charcot-Marie-Tooth–Like Neuropathy in Transgenic Mice

In peripheral nerve myelin, the intraperiod line results from compaction of the extracellular space due to homophilic adhesion between extracellular domains (ECD) of the protein zero (P(0)) glycoprotein. Point mutations in this region of P(0) cause human hereditary demyelinating neuropathies such as...

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Main Authors: Previtali, Stefano C., Quattrini, Angelo, Fasolini, Marina, Panzeri, Maria Carla, Villa, Antonello, Filbin, Marie T., Li, Wenhui, Chiu, Shing-Yan, Messing, Albee, Wrabetz, Lawrence, Feltri, M. Laura
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2000
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174348/
https://ncbi.nlm.nih.gov/pubmed/11086005
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