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Protein Kinase Cδ and Calmodulin Regulate Epidermal Growth Factor Receptor Recycling from Early Endosomes through Arp2/3 Complex and Cortactin

The intracellular trafficking of the epidermal growth factor receptor (EGFR) is regulated by a cross-talk between calmodulin (CaM) and protein kinase Cδ (PKCδ). On inhibition of CaM, PKCδ promotes the formation of enlarged early endosomes and blocks EGFR recycling and degradation. Here, we show that...

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Detalhes bibliográficos
Main Authors: Lladó, Anna, Timpson, Paul, Vilà de Muga, Sandra, Moretó, Jemina, Pol, Albert, Grewal, Thomas, Daly, Roger J., Enrich, Carlos, Tebar, Francesc
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174165/
https://ncbi.nlm.nih.gov/pubmed/17959830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-05-0411
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