Protein Kinase Cδ and Calmodulin Regulate Epidermal Growth Factor Receptor Recycling from Early Endosomes through Arp2/3 Complex and Cortactin

The intracellular trafficking of the epidermal growth factor receptor (EGFR) is regulated by a cross-talk between calmodulin (CaM) and protein kinase Cδ (PKCδ). On inhibition of CaM, PKCδ promotes the formation of enlarged early endosomes and blocks EGFR recycling and degradation. Here, we show that...

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Hauptverfasser: Lladó, Anna, Timpson, Paul, Vilà de Muga, Sandra, Moretó, Jemina, Pol, Albert, Grewal, Thomas, Daly, Roger J., Enrich, Carlos, Tebar, Francesc
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2008
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174165/
https://ncbi.nlm.nih.gov/pubmed/17959830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-05-0411
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