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KCNE Peptides Differently Affect Voltage Sensor Equilibrium and Equilibration Rates in KCNQ1 K(+) Channels

KCNQ1 voltage-gated K(+) channels assemble with the family of KCNE type I transmembrane peptides to afford membrane-embedded complexes with diverse channel gating properties. KCNQ1/KCNE1 complexes generate the very slowly activating cardiac I(Ks) current, whereas assembly with KCNE3 produces a const...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rocheleau, Jessica M., Kobertz, William R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174159/
https://ncbi.nlm.nih.gov/pubmed/18079560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200709816
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