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Human TPX2 is required for targeting Aurora-A kinase to the spindle
Aurora-A is a serine-threonine kinase implicated in the assembly and maintenance of the mitotic spindle. Here we show that human Aurora-A binds to TPX2, a prominent component of the spindle apparatus. TPX2 was identified by mass spectrometry as a major protein coimmunoprecipitating specifically with...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2174010/ https://ncbi.nlm.nih.gov/pubmed/12177045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200204155 |
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