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FGF signaling targets the pRb-related p107 and p130 proteins to induce chondrocyte growth arrest
Unregulated FGF signaling affects endochondral ossification and long bone growth, causing several genetic forms of human dwarfism. One major mechanism by which FGFs regulate endochondral bone growth is through their inhibitory effect on chondrocyte proliferation. Because mice with targeted mutations...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2174007/ https://ncbi.nlm.nih.gov/pubmed/12177046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200205025 |
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