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A network of transcriptional and signaling events is activated by FGF to induce chondrocyte growth arrest and differentiation
Activating mutations in FGF receptor 3 (FGFR3) cause several human dwarfism syndromes by affecting both chondrocyte proliferation and differentiation. Using microarray and biochemical analyses of FGF-treated rat chondrosarcoma chondrocytes, we show that FGF inhibits chondrocyte proliferation by init...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Rockefeller University Press
2003
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172997/ https://ncbi.nlm.nih.gov/pubmed/12821644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200302075 |
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