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FGF inhibits the activity of the cyclin B1/CDK1 kinase to induce a transient G(2) arrest in RCS chondrocytes

Fibroblast growth factors (FGFs) negatively regulate long bone development by inhibiting the proliferation of chondrocytes that accumulate in the G(1) phase of the cycle following FGF treatment. Here we report that FGF also causes a striking but transient delay in mitotic entry in RCS chondrocytes b...

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Bibliografische gegevens
Hoofdauteurs: Tran, Tri, Kolupaeva, Victoria, Basilico, Claudio
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Landes Bioscience 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055189/
https://ncbi.nlm.nih.gov/pubmed/21051949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.21.13671
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