FGF inhibits the activity of the cyclin B1/CDK1 kinase to induce a transient G(2) arrest in RCS chondrocytes

Fibroblast growth factors (FGFs) negatively regulate long bone development by inhibiting the proliferation of chondrocytes that accumulate in the G(1) phase of the cycle following FGF treatment. Here we report that FGF also causes a striking but transient delay in mitotic entry in RCS chondrocytes b...

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Bibliographic Details
Main Authors: Tran, Tri, Kolupaeva, Victoria, Basilico, Claudio
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055189/
https://ncbi.nlm.nih.gov/pubmed/21051949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.21.13671
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