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FGF inhibits the activity of the cyclin B1/CDK1 kinase to induce a transient G(2) arrest in RCS chondrocytes

Fibroblast growth factors (FGFs) negatively regulate long bone development by inhibiting the proliferation of chondrocytes that accumulate in the G(1) phase of the cycle following FGF treatment. Here we report that FGF also causes a striking but transient delay in mitotic entry in RCS chondrocytes b...

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Autori principali: Tran, Tri, Kolupaeva, Victoria, Basilico, Claudio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055189/
https://ncbi.nlm.nih.gov/pubmed/21051949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.21.13671
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