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Synaptotagmins I and II mediate entry of botulinum neurotoxin B into cells

Botulinum neurotoxins (BoNTs) cause botulism by entering neurons and cleaving proteins that mediate neurotransmitter release; disruption of exocytosis results in paralysis and death. The receptors for BoNTs are thought to be composed of both proteins and gangliosides; however, protein components tha...

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Autors principals: Dong, Min, Richards, David A., Goodnough, Michael C., Tepp, William H., Johnson, Eric A., Chapman, Edwin R.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173968/
https://ncbi.nlm.nih.gov/pubmed/14504267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200305098
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