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FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons
Developing sympathetic neurons die by apoptosis when deprived of NGF. BIM, a BH3-only member of the BCL-2 family, is induced after NGF withdrawal in these cells and contributes to NGF withdrawal–induced death. Here, we have investigated the involvement of the Forkhead box, class O (FOXO) subfamily o...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Rockefeller University Press
2003
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2173804/ https://ncbi.nlm.nih.gov/pubmed/12913110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200303026 |
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