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Compartmentalized megakaryocyte death generates functional platelets committed to caspase-independent death

Caspase-directed apoptosis usually fragments cells, releasing nonfunctional, prothrombogenic, membrane-bound apoptotic bodies marked for rapid engulfment by macrophages. Blood platelets are functional anucleate cells generated by specialized fragmentation of their progenitors, megakaryocytes (MKs),...

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Detalhes bibliográficos
Main Authors: Clarke, Murray C.H., Savill, John, Jones, David B., Noble, Brendon S., Brown, Simon B.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173731/
https://ncbi.nlm.nih.gov/pubmed/12591916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200210111
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