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Compartmentalized megakaryocyte death generates functional platelets committed to caspase-independent death
Caspase-directed apoptosis usually fragments cells, releasing nonfunctional, prothrombogenic, membrane-bound apoptotic bodies marked for rapid engulfment by macrophages. Blood platelets are functional anucleate cells generated by specialized fragmentation of their progenitors, megakaryocytes (MKs),...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2173731/ https://ncbi.nlm.nih.gov/pubmed/12591916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200210111 |
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