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Loss of proteolytically processed filaggrin caused by epidermal deletion of Matriptase/MT-SP1

Profilaggrin is a large epidermal polyprotein that is proteolytically processed during keratinocyte differentiation to release multiple filaggrin monomer units as well as a calcium-binding regulatory NH(2)-terminal filaggrin S-100 protein. We show that epidermal deficiency of the transmembrane serin...

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Hlavní autoři: List, Karin, Szabo, Roman, Wertz, Philip W., Segre, Julie, Haudenschild, Christian C., Kim, Soo-Youl, Bugge, Thomas H.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2003
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173680/
https://ncbi.nlm.nih.gov/pubmed/14638864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200304161
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