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Influence of cargo size on Ran and energy requirements for nuclear protein import

Previous work has shown that the transport of some small protein cargoes through the nuclear pore complex (NPC) can occur in vitro in the absence of nucleoside triphosphate hydrolysis. We now demonstrate that in the importin α/β and transportin import pathways, efficient in vitro transport of large...

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Autors principals: Lyman, Susan K., Guan, Tinglu, Bednenko, Janna, Wodrich, Harald, Gerace, Larry
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173498/
https://ncbi.nlm.nih.gov/pubmed/12370244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200204163
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