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Influence of cargo size on Ran and energy requirements for nuclear protein import

Previous work has shown that the transport of some small protein cargoes through the nuclear pore complex (NPC) can occur in vitro in the absence of nucleoside triphosphate hydrolysis. We now demonstrate that in the importin α/β and transportin import pathways, efficient in vitro transport of large...

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Autori principali: Lyman, Susan K., Guan, Tinglu, Bednenko, Janna, Wodrich, Harald, Gerace, Larry
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173498/
https://ncbi.nlm.nih.gov/pubmed/12370244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200204163
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