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Cytosolic free Ca(2+) changes and calpain activation are required for β integrin–accelerated phagocytosis by human neutrophils

Phagocytosis of microbes coated with opsonins such as the complement component C3bi is the key activity of neutrophils. However, the mechanism by which opsonins enhance the rate of phagocytosis by these cells is unknown and has been difficult to study, partly because of the problem of observing and...

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Autores principales: Dewitt, Sharon, Hallett, Maurice B.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173489/
https://ncbi.nlm.nih.gov/pubmed/12379807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200206089
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