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Ca(2+) and calpain control membrane expansion during the rapid cell spreading of neutrophils
Following adherence of neutrophils to the endothelium, neutrophils undergo a major morphological change that is a necessary prelude to their extravasation. We show here that this shape change is triggered by an elevation of cytosolic inositol (1,4,5)-trisphosphate (IP(3)), to provoke physiological C...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Company of Biologists
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3795336/ https://ncbi.nlm.nih.gov/pubmed/23943875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.124917 |
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