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Ca(2+) and calpain control membrane expansion during the rapid cell spreading of neutrophils

Following adherence of neutrophils to the endothelium, neutrophils undergo a major morphological change that is a necessary prelude to their extravasation. We show here that this shape change is triggered by an elevation of cytosolic inositol (1,4,5)-trisphosphate (IP(3)), to provoke physiological C...

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Detalhes bibliográficos
Main Authors: Dewitt, Sharon, Francis, Robert J., Hallett, Maurice B.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795336/
https://ncbi.nlm.nih.gov/pubmed/23943875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.124917
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