Staurosporine clamps cytosolic free Ca2+ concentrations of human neutrophils.

The present studies indicate that 50 nM-10 microM-staurosporine increased cytosolic free Ca2+ concentrations ([Ca2+]i) of fura-2-loaded neutrophils in a non-linear manner. The rise in [Ca2+]i was rapid, reaching a plateau (e.g. to 0.4 microM with 1 microM-staurosporine) within 30 s, and was maintain...

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Hlavní autoři: Wong, K, Kwan-Yeung, L, Turkson, J
Médium: Artigo
Jazyk:Inglês
Vydáno: 1992
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1131063/
https://ncbi.nlm.nih.gov/pubmed/1575694
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