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A role of topoisomerase II in linking DNA replication to chromosome condensation

The condensin complex and topoisomerase II (topo II) have different biochemical activities in vitro, and both are required for mitotic chromosome condensation. We have used Xenopus egg extracts to investigate the functional interplay between condensin and topo II in chromosome condensation. When unr...

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Autors principals: Cuvier, Olivier, Hirano, Tatsuya
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173373/
https://ncbi.nlm.nih.gov/pubmed/12604590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200209023
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