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Regulation of cytochrome c oxidase activity by c-Src in osteoclasts

The function of the nonreceptor tyrosine kinase c-Src as a plasma membrane–associated molecular effector of a variety of extracellular stimuli is well known. Here, we show that c-Src is also present within mitochondria, where it phosphorylates cytochrome c oxidase (Cox). Deleting the c-src gene redu...

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Détails bibliographiques
Auteurs principaux: Miyazaki, Tsuyoshi, Neff, Lynn, Tanaka, Sakae, Horne, William C., Baron, Roland
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173369/
https://ncbi.nlm.nih.gov/pubmed/12615910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200209098
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