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AP-1 binding to sorting signals and release from clathrin-coated vesicles is regulated by phosphorylation
The adaptor protein complex-1 (AP-1) sorts and packages membrane proteins into clathrin-coated vesicles (CCVs) at the TGN and endosomes. Here we show that this process is highly regulated by phosphorylation of AP-1 subunits. Cell fractionation studies revealed that membrane-associated AP-1 differs f...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Rockefeller University Press
2003
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2173368/ https://ncbi.nlm.nih.gov/pubmed/12604586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200211080 |
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