Muscle-specific RING finger-1 interacts with titin to regulate sarcomeric M-line and thick filament structure and may have nuclear functions via its interaction with glucocorticoid modulatory element binding protein-1

The COOH-terminal A168–170 region of the giant sarcomeric protein titin interacts with muscle-specific RING finger-1 (MURF-1). To investigate the functional significance of this interaction, we expressed green fluorescent protein fusion constructs encoding defined fragments of titin's M-line re...

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Hauptverfasser: McElhinny, Abigail S., Kakinuma, Kazumi, Sorimachi, Hiroyuki, Labeit, Siegfried, Gregorio, Carol C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2002
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173255/
https://ncbi.nlm.nih.gov/pubmed/11927605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200108089
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