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TGFβ receptor internalization into EEA1-enriched early endosomes: role in signaling to Smad2

Transforming growth factor (TGF)β is an important physiological regulator of cellular growth and differentiation. It activates a receptor threonine/serine kinase that phosphorylates the transcription factor Smad2, which then translocates into the nucleus to trigger specific transcriptional events. H...

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Sonraí Bibleagrafaíochta
Main Authors: Hayes, Susan, Chawla, Anil, Corvera, Silvia
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Rockefeller University Press 2002
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173232/
https://ncbi.nlm.nih.gov/pubmed/12356868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200204088
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