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Hyaluronan–CD44 interaction hampers migration of osteoclast-like cells by down-regulating MMP-9

Osteoclast (OC) precursors migrate to putative sites of bone resorption to form functionally active, multinucleated cells. The preOC FLG 29.1 cells, known to be capable of irreversibly differentiating into multinucleated OC-like cells, displayed several features of primary OCs, including expression...

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Detalhes bibliográficos
Main Authors: Spessotto, Paola, Rossi, Francesca Maria, Degan, Massimo, Di Francia, Raffaele, Perris, Roberto, Colombatti, Alfonso, Gattei, Valter
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173214/
https://ncbi.nlm.nih.gov/pubmed/12235127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200202120
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