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Design and syntheses of hyaluronan oligosaccharide conjugates as inhibitors of CD44-Hyaluronan binding

Hyaluronan (HA) is an integral component of the extracellular matrix. Its interactions with a cell surface receptor CD44 has been shown to play important roles in a variety of biological events including cell proliferation and metastasis. As multivalent CD44-HA binding is critical for downstream sig...

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Vydáno v:Glycoconj J
Hlavní autoři: Lu, Xiaowei, Huang, Xuefei
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712157/
https://ncbi.nlm.nih.gov/pubmed/25997408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10719-015-9597-3
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