MMP-13 stimulates osteoclast differentiation and activation in tumour breast bone metastases

INTRODUCTION: The increased bone degradation in osteolytic metastases depends on stimulation of mature osteoclasts and on continuous differentiation of new pre-osteoclasts. Metalloproteinases (MMP)-13 is expressed in a broad range of primary malignant tumours and it is emerging as a novel biomarker....

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Detalhes bibliográficos
Main Authors: Pivetta, Eliana, Scapolan, Martina, Pecolo, Marina, Wassermann, Bruna, Abu-Rumeileh, Imad, Balestreri, Luca, Borsatti, Eugenio, Tripodo, Claudio, Colombatti, Alfonso, Spessotto, Paola
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262218/
https://ncbi.nlm.nih.gov/pubmed/22032644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3047
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