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Rapid microtubule-independent dynamics of Cdc20 at kinetochores and centrosomes in mammalian cells

Cdc20 is a substrate adaptor and activator of the anaphase-promoting complex/cyclosome (APC/C), the E3 ubiquitin ligase whose activity is required for anaphase onset and exit from mitosis. A green fluorescent protein derivative, Cdc20–GFP, bound to centrosomes throughout the cell cycle and to kineto...

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Autori principali: Kallio, Marko J., Beardmore, Victoria A., Weinstein, Jasminder, Gorbsky, Gary J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173153/
https://ncbi.nlm.nih.gov/pubmed/12196507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200201135
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