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DNA replication is required for the checkpoint response to damaged DNA in Xenopus egg extracts

Alkylating agents, such as methyl methanesulfonate (MMS), damage DNA and activate the DNA damage checkpoint. Although many of the checkpoint proteins that transduce damage signals have been identified and characterized, the mechanism that senses the damage and activates the checkpoint is not yet und...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Stokes, Matthew P., Van Hatten, Ruth, Lindsay, Howard D., Michael, W. Matthew
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The Rockefeller University Press 2002
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173144/
https://ncbi.nlm.nih.gov/pubmed/12213834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200204127
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