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DNA replication is required for the checkpoint response to damaged DNA in Xenopus egg extracts
Alkylating agents, such as methyl methanesulfonate (MMS), damage DNA and activate the DNA damage checkpoint. Although many of the checkpoint proteins that transduce damage signals have been identified and characterized, the mechanism that senses the damage and activates the checkpoint is not yet und...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2173144/ https://ncbi.nlm.nih.gov/pubmed/12213834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200204127 |
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