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DNA damage-induced replication arrest in Xenopus egg extracts

Chromosomal replication is sensitive to the presence of DNA-damaging alkylating agents, such as methyl methanesulfonate (MMS). MMS is known to inhibit replication though activation of the DNA damage checkpoint and through checkpoint-independent slowing of replication fork progression. Using Xenopus...

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Detalhes bibliográficos
Main Authors: Stokes, Matthew P., Michael, W. Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173517/
https://ncbi.nlm.nih.gov/pubmed/14581453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200306006
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