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DNA damage-induced replication arrest in Xenopus egg extracts

Chromosomal replication is sensitive to the presence of DNA-damaging alkylating agents, such as methyl methanesulfonate (MMS). MMS is known to inhibit replication though activation of the DNA damage checkpoint and through checkpoint-independent slowing of replication fork progression. Using Xenopus...

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Sonraí Bibleagrafaíochta
Main Authors: Stokes, Matthew P., Michael, W. Matthew
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Rockefeller University Press 2003
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173517/
https://ncbi.nlm.nih.gov/pubmed/14581453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200306006
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