The PEBP2βMYH11 fusion created by Inv(16)(p13;q22) in myeloid leukemia impairs neutrophil maturation and contributes to granulocytic dysplasia

Chromosomal translocations involving the genes encoding the alpha and beta subunits of the Pebp2/Cbf transcription factor have been associated with human acute myeloid leukemia and the preleukemic condition, myelodysplasia. Inv(16)(p13;q22) fuses the gene encoding the beta subunit of Pebp2 to the MY...

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Detalles Bibliográficos
Autores principales: Kogan, Scott C., Lagasse, Eric, Atwater, Susan, Bae, Suk-chul, Weissman, Irving, Ito, Yoshiaki, Bishop, J. Michael
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1998
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC21731/
https://ncbi.nlm.nih.gov/pubmed/9751756
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