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Crystal structure of the TSP-1 type 1 repeats: a novel layered fold and its biological implication
Thrombospondin-1 (TSP-1) contains three type 1 repeats (TSRs), which mediate cell attachment, glycosaminoglycan binding, inhibition of angiogenesis, activation of TGFβ, and inhibition of matrix metalloproteinases. The crystal structure of the TSRs reported in this article reveals a novel, antiparall...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
2002
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2173040/ https://ncbi.nlm.nih.gov/pubmed/12391027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200206062 |
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