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The Structures of the Thrombospondin-1 N-Terminal Domain and Its Complex with a Synthetic Pentameric Heparin
The N-terminal domain of thrombospondin-1 (TSPN-1) mediates the protein’s interaction with (1) glycosaminoglycans, calreticulin, and integrins during cellular adhesion, (2) low-density lipoprotein receptor-related protein during uptake and clearance, and (3) fibrinogen during platelet aggregation. T...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2896259/ https://ncbi.nlm.nih.gov/pubmed/16407063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2005.09.017 |
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