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The crystal structure of the signature domain of cartilage oligomeric matrix protein: implications for collagen, glycosaminoglycan and integrin binding

Cartilage oligomeric matrix protein (COMP), or thrombospondin-5 (TSP-5), is a secreted glycoprotein that is important for growth plate organization and function. Mutations in COMP cause two skeletal dysplasias, pseudoachondroplasia (PSACH) and multiple epiphyseal dysplasia (EDM1). In this study, we...

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Hlavní autoři: Tan, Kemin, Duquette, Mark, Joachimiak, Andrzej, Lawler, Jack
Médium: Artigo
Jazyk:Inglês
Vydáno: The Federation of American Societies for Experimental Biology 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717772/
https://ncbi.nlm.nih.gov/pubmed/19276170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-128090
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