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Neural cell adhesion molecule (NCAM) association with PKCβ(2) via βI spectrin is implicated in NCAM-mediated neurite outgrowth

In hippocampal neurons and transfected CHO cells, neural cell adhesion molecule (NCAM) 120, NCAM140, and NCAM180 form Triton X-100–insoluble complexes with βI spectrin. Heteromeric spectrin (αIβI) binds to the intracellular domain of NCAM180, and isolated spectrin subunits bind to both NCAM180 and N...

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Auteurs principaux: Leshchyns'ka, Iryna, Sytnyk, Vladimir, Morrow, Jon S., Schachner, Melitta
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172933/
https://ncbi.nlm.nih.gov/pubmed/12743109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200303020
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