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Proprotein convertase cleavage liberates a fibrillogenic fragment of a resident glycoprotein to initiate melanosome biogenesis

Lysosome-related organelles are cell type–specific intracellular compartments with distinct morphologies and functions. The molecular mechanisms governing the formation of their unique structural features are not known. Melanosomes and their precursors are lysosome-related organelles that are charac...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Berson, Joanne F., Theos, Alexander C., Harper, Dawn C., Tenza, Danielle, Raposo, Graça, Marks, Michael S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172928/
https://ncbi.nlm.nih.gov/pubmed/12732614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200302072
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