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Proprotein convertase cleavage liberates a fibrillogenic fragment of a resident glycoprotein to initiate melanosome biogenesis

Lysosome-related organelles are cell type–specific intracellular compartments with distinct morphologies and functions. The molecular mechanisms governing the formation of their unique structural features are not known. Melanosomes and their precursors are lysosome-related organelles that are charac...

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Autori principali: Berson, Joanne F., Theos, Alexander C., Harper, Dawn C., Tenza, Danielle, Raposo, Graça, Marks, Michael S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172928/
https://ncbi.nlm.nih.gov/pubmed/12732614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200302072
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