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Shear stress–induced endothelial cell polarization is mediated by Rho and Rac but not Cdc42 or PI 3-kinases

Shear stress induces endothelial polarization and migration in the direction of flow accompanied by extensive remodeling of the actin cytoskeleton. The GTPases RhoA, Rac1, and Cdc42 are known to regulate cell shape changes through effects on the cytoskeleton and cell adhesion. We show here that all...

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Detaylı Bibliyografya
Asıl Yazarlar: Wojciak-Stothard, Beata, Ridley, Anne J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2003
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172912/
https://ncbi.nlm.nih.gov/pubmed/12719476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200210135
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