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RPTP-α acts as a transducer of mechanical force on α(v)/β(3)-integrin–cytoskeleton linkages
Cell motility on ECM critically depends on the cellular response to force from the matrix. We find that force-dependent reinforcement of α(v)/β(3)-integrin–mediated cell–matrix connections requires the receptor-like tyrosine phosphatase α (RPTPα). RPTPα colocalizes with α(v)-integrins at the leading...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172891/ https://ncbi.nlm.nih.gov/pubmed/12682088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200211061 |
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