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Rigidity Sensing at the Leading Edge through α(v)β(3) Integrins and RPTPα
Cells require optimal substrate stiffness for normal function and differentiation. The mechanisms for sensing matrix rigidity and durotaxis, however, are not clear. Here we showed that control, Shp2(−/−), integrin β1(−/−), and talin1(−/−) cell lines all spread to a threefold greater area on fibronec...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1367329/ https://ncbi.nlm.nih.gov/pubmed/16339875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.072462 |
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