Laddar...

Rigidity Sensing at the Leading Edge through α(v)β(3) Integrins and RPTPα

Cells require optimal substrate stiffness for normal function and differentiation. The mechanisms for sensing matrix rigidity and durotaxis, however, are not clear. Here we showed that control, Shp2(−/−), integrin β1(−/−), and talin1(−/−) cell lines all spread to a threefold greater area on fibronec...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Jiang, Guoying, Huang, Angela H., Cai, Yunfei, Tanase, Monica, Sheetz, Michael P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Biophysical Society 2006
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367329/
https://ncbi.nlm.nih.gov/pubmed/16339875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.072462
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!