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Local signaling by the EGF receptor

Differing spatial scales of signaling cascades are critical for cell orientation during chemotactic responses. We used biotin EGF bound to streptavidin-coupled magnetic beads to locally stimulate cells overexpressing the EGF receptor. We have found that EGF-induced actin polymerization remains local...

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Autors principals: Kempiak, Stephan J., Yip, Shu-Chin, Backer, Jonathan M., Segall, Jeffrey E.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172819/
https://ncbi.nlm.nih.gov/pubmed/12952932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200303144
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