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Characterization of the signal that directs Bcl-x(L), but not Bcl-2, to the mitochondrial outer membrane
It is assumed that the survival factors Bcl-2 and Bcl-x(L) are mainly functional on mitochondria and therefore must contain mitochondrial targeting sequences. Here we show, however, that only Bcl-x(L) is specifically targeted to the mitochondrial outer membrane (MOM) whereas Bcl-2 distributes on sev...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172731/ https://ncbi.nlm.nih.gov/pubmed/12515824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200210084 |
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