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How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?

The mitochondrial pathway of apoptosis proceeds when molecules sequestered between the outer and inner mitochondrial membranes are released to the cytosol by mitochondrial outer membrane permeabilization (MOMP). This process is controlled by the BCL-2 family, which is composed of both pro- and anti-...

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Detalhes bibliográficos
Main Authors: Chipuk, Jerry E., Green, Douglas R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242477/
https://ncbi.nlm.nih.gov/pubmed/18314333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2008.01.007
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