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Decreased apoptosome activity with neuronal differentiation sets the threshold for strict IAP regulation of apoptosis
Despite the potential of the inhibitor of apoptosis proteins (IAPs) to block cytochrome c–dependent caspase activation, the critical function of IAPs in regulating mammalian apoptosis remains unclear. We report that the ability of endogenous IAPs to effectively regulate caspase activation depends on...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Rockefeller University Press
2004
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172554/ https://ncbi.nlm.nih.gov/pubmed/15504912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200406073 |
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