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Plexin-B1/RhoGEF–mediated RhoA activation involves the receptor tyrosine kinase ErbB-2

Plexins are widely expressed transmembrane proteins that mediate the effects of semaphorins. The molecular mechanisms of plexin-mediated signal transduction are still rather unclear. Plexin-B1 has recently been shown to mediate activation of RhoA through a stable interaction with the Rho guanine nuc...

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Autores principales: Swiercz, Jakub M., Kuner, Rohini, Offermanns, Stefan
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172401/
https://ncbi.nlm.nih.gov/pubmed/15210733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200312094
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