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Deregulation of cyclin E in human cells interferes with prereplication complex assembly
Deregulation of cyclin E expression has been associated with a broad spectrum of human malignancies. Analysis of DNA replication in cells constitutively expressing cyclin E at levels similar to those observed in a subset of tumor-derived cell lines indicates that initiation of replication and possib...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172392/ https://ncbi.nlm.nih.gov/pubmed/15197178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200404092 |
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