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Cyclin E Deregulation Promotes Loss of Specific Genomic Regions

Cell cycle progression is regulated by the cyclin-dependent kinase (Cdk) family of protein kinases, so named because their activation depends on association with regulatory subunits known as cyclins [1]. Cyclin E normally accumulates at the G1/S boundary, where it promotes S phase entry and progress...

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Detalhes bibliográficos
Publicado no:Curr Biol
Main Authors: Teixeira, Leonardo K., Wang, Xianlong, Li, Yongjiang, Ekholm-Reed, Susanna, Wu, Xiaohua, Wang, Pei, Reed, Steven I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4439338/
https://ncbi.nlm.nih.gov/pubmed/25959964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2015.03.022
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