Cyclin K regulates prereplicative complex assembly to promote mammalian cell proliferation

The assembly of prereplicative complex (pre-RC) during G1 phase must be tightly controlled to sustain cell proliferation and maintain genomic stability. Mechanisms to prevent pre-RC formation in G2/M and S phases are well appreciated, whereas how cells ensure efficient pre-RC assembly during G1 is l...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Lei, Tingjun, Zhang, Peixuan, Zhang, Xudong, Xiao, Xue, Zhang, Jingli, Qiu, Tong, Dai, Qian, Zhang, Yujun, Min, Ling, Li, Qian, Yin, Rutie, Ding, Ping, Li, Ni, Qu, Yi, Mu, Dezhi, Qin, Jun, Zhu, Xiaofeng, Xiao, Zhi-Xiong, Li, Qintong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5951916/
https://ncbi.nlm.nih.gov/pubmed/29760377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04258-w
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