BCL-6 mutations in normal germinal center B cells: Evidence of somatic hypermutation acting outside Ig loci

The molecular mechanism involved in the process of antigen-driven somatic hypermutation of Ig genes is unknown, but it is commonly believed that this mechanism is restricted to the Ig loci. B cell lymphomas commonly display multiple somatic mutations clustering in the 5′-regulatory region of BCL-6,...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Pasqualucci, Laura, Migliazza, Anna, Fracchiolla, Nicola, William, Christopher, Neri, Antonino, Baldini, Luca, Chaganti, R. S. K., Klein, Ulf, Küppers, Ralf, Rajewsky, Klaus, Dalla-Favera, Riccardo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 1998
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC21723/
https://ncbi.nlm.nih.gov/pubmed/9751748
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