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The Abl-related gene (Arg) requires its F-actin–microtubule cross-linking activity to regulate lamellipodial dynamics during fibroblast adhesion

Microtubules (MTs) help establish and maintain cell polarity by promoting actin-dependent membrane protrusion at the leading edge of the cell, but the molecular mechanisms that mediate cross-talk between actin and MTs during this process are unclear. We demonstrate that the Abl-related gene (Arg) no...

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Autors principals: Miller, Ann L., Wang, Yinxiang, Mooseker, Mark S., Koleske, Anthony J.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172189/
https://ncbi.nlm.nih.gov/pubmed/15138293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200308055
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