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Arg/Abl2 Modulates the Affinity and Stoichiometry of Binding of Cortactin to F-Actin
[Image: see text] The Abl family nonreceptor tyrosine kinase Arg/Abl2 interacts with cortactin, an Arp2/3 complex activator, to promote actin-driven cell edge protrusion. Both Arg and cortactin bind directly to filamentous actin (F-actin). While protein– protein interactions between Arg and cortacti...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3556572/ https://ncbi.nlm.nih.gov/pubmed/22849492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300722t |
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