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Arg/Abl2 Modulates the Affinity and Stoichiometry of Binding of Cortactin to F-Actin

[Image: see text] The Abl family nonreceptor tyrosine kinase Arg/Abl2 interacts with cortactin, an Arp2/3 complex activator, to promote actin-driven cell edge protrusion. Both Arg and cortactin bind directly to filamentous actin (F-actin). While protein– protein interactions between Arg and cortacti...

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Bibliografske podrobnosti
Main Authors: MacGrath, Stacey M., Koleske, Anthony J.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556572/
https://ncbi.nlm.nih.gov/pubmed/22849492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300722t
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