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SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes

TCF and SOX proteins belong to the high mobility group box transcription factor family. Whereas TCFs, the transcriptional effectors of the Wnt pathway, have been widely implicated in the development, homeostasis and disease of the intestine epithelium, little is known about the function of the SOX p...

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Autors principals: Blache, Philippe, van de Wetering, Marc, Duluc, Isabelle, Domon, Claire, Berta, Philippe, Freund, Jean-Noël, Clevers, Hans, Jay, Philippe
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172132/
https://ncbi.nlm.nih.gov/pubmed/15240568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200311021
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